"The only time an aircraft has too much fuel on board is when it is on fire." - Sir Charles Kingsford Smith, sometime before his death in the 1920s
"If you can't afford to do something right, then be darn sure you can afford to do it wrong." - Charlie Nelson
"When a prang seems inevitable, endeavor to strike the softest, cheapest object in the vicinity, as slowly and gently as possible." - Advice given to RAF pilots during WWII.
Basic Flying Rule: Try to stay in the middle of the air. Do not go near the edges of it. The edges of the air can be recognized by the appearance of ground, buildings, sea, trees and interstellar space. It is much more difficult to fly there.
For the pilot the best resolution of an anxiety chain problem appears to be behavioral therapy. This means gradual desensitizing by exposure to what is creating a concern. Exercise seems to help as does yoga. Any chemical solution will not let you fly legally.